Product Usage
This product is intended for research purposes only. All product information available on this website is for educational purposes only. This product is not intended for consumption or bodily introduction of any kind. It should only be handled by licensed and qualified professionals. It is not a drug, food, or cosmetic, and must not be misbranded, misused, or mislabeled as such.
α-Klotho MAB
PURITY ≥98%/LOT LL-0824/HPLC VERIFIED
α-Klotho MAB — Klotho Pathway Antibody Fragment. 10 mcg (x2 vials).
FDA Disclaimer: The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease. All products are for laboratory developmental research USE ONLY. Not intended for consumption of any kind.
03 / Research Context
Research context
Alpha-Klotho Monoclonal Antibody Fragment is a research-grade antibody targeting the Klotho protein — a transmembrane protein first identified as an aging-suppressor gene. Klotho deficiency accelerates aging phenotypes including arteriosclerosis, osteoporosis, and cognitive decline, while overexpression extends lifespan by 20-30% in animal models. α-Klotho circulates as a soluble form that regulates calcium/phosphate metabolism, inhibits insulin/IGF-1 signaling, suppresses Wnt pathway-driven aging, and protects against oxidative stress. This antibody fragment enables research into Klotho pathway modulation and longevity.
Key research areas
- Targets the Klotho aging-suppressor pathway
- Klotho overexpression extends lifespan 20-30%
- Protects against cognitive decline and neurodegeneration
- Regulates calcium/phosphate metabolism
- Suppresses Wnt-driven aging pathways
- Antioxidant and anti-arteriosclerotic properties
Handling & reconstitution
Supplied as a lyophilized powder. Bacteriostatic water is the recommended solvent for reconstitution in research applications. Store unreconstituted product at -20°C; reconstituted solutions should be stored at -20°C and used within 14–30 days.
Research use only. Not for human consumption.
Product specifications
| Type | Klotho Pathway Antibody Fragment |
| Composition | 10 mcg (x2 vials) |
| Purity | 98%+ |
| Appearance | Lyophilized Powder |
| Storage | -20°C |
